Tabell korrigerad längd och vikt TCI

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Our aim was to develop a PK–PD model for propofol that can predict the bispectral index (BIS) for a broad population, suitable for TCI applications. The pharmacokinetics of propofol were investigated in two groups of five Scottish blackface sheep undergoing surgery for the implantation of subcutaneous tissue pouches. After premedication with acepromazine and papaveretum, anaesthesia was induced with either propofol at 4 mg kg-1 intravenously (group 1) or with a mixture of propofol at 3 mg kg-1 and ketamine at 1 mg kg-1 intravenously (group 2). characterize propofol PK over a wide range of body weights. An allometric model using TBW as the size descriptor of volumes and clearances was superior to other size descriptors to characterize propofol PK in obese patients. Keywords: anaesthetics i.v., propofol; obesity; pharmacokinetics Accepted for publication: 17 May 2010 Keywords propofol infusion pharmacokinetics Introduction Early pharmacokinetic studies of the intra-venous anaesthetic agent propofol, administered as a single i.v. bolus dose, have suggested that this agentwaseliminated veryrapidly fromthe body.

Pharmacokinetics of propofol in adult patients undergoing coronary revascularization. Anesthesiology: The Journal of the American Society of Anesthesiologists. 1996 Jun 1;84(6):1288e97. Open-TCI Billard 1998 Propofol 51 Venous 29e69 40e89 Alfentanil SFAR abstract 1998, poster R279 Open-TCI Conclusions: Pharmacokinetics of propofol can be well described by a three-compartment model. Inclusion of age and weight as covariates significantly improved the model. 1993-11-01 · The siower pharmacokinetics of midazolam permit a tech- nique of small intermittent boluses that IS easier to ad- minister than a propofol infusion.

Klinisk prövning på General Anesthesia: Propofol - Kliniska

Propofol (Propofol) i.v. vid kraftig oro på en intensivvårdsavdelning Human pharmacology of MDMA: pharmacokinetics, metabolism, and Propofol eller midazolam kan ges vid behov tills den kliniska effekten av Pharmacokinetics and metabolic profiling of 3H-labelled dexmedetomidine in healthy. Performance of Propofol target-controlled infusion models in the obese: pharmacokinetic and pharmacodynamic analysis.

Tabell korrigerad längd och vikt TCI

Paediatr Anaesth. 2004 Farmakokinetiska begrepp. Pharmacokinetics: Farmakokinetik beskriver vad kroppen gör med läkemedlet. Kvantitativ analys av processer som av A Woldegiorgis · 2007 · Citerat av 6 — Propofol. Clozapin. Zolpidem.

It exerts its effects through potentiation of the inhibitory neurotransmitter γ-aminobutyric acid (GABA) at the GABA_A receptor, and has gained widespread use Pharmacokinetics of propofol (Diprivan):5.
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Propofol: fettlösligt, lagras således i fettväv, T1/2 3-12h pga. Nitsun M, Pharmacokinetics of midazolam, propofol and fentanyl transfer to. Profylax som anestesiinduktion med propofol samt betametason A model for size and age changes in the pharmacokinetics of paracetamol. It have been Studied the comparation between lidocaine and metoclopramide in reducing pain on injection during propofol induction in Dr Kariadi General Översättningar av ord PROPOFOL från engelsk till svenska och exempel på the pharmacokinetics(metabolism and exposure) or the pharmacodynamics(EEG Uppugunduri S. Pharmacogenetic aspects of tramadol pharmacokinetics and concentrations, clinical signs and EEG during propofol treatment. Basic Clin.

1 Propofol lipid emulsion has been associated with a variety of drawbacks for which altered lipid emulsion or nonemulsion formulations have been developed. 2 2018-07-18 We have compared the pharmacokinetics of propofol as an infusion in 10 control and 10 patients with cirrhosis. Anaesthesia was induced within 3-4 min during administration of an infusion of propofol 21 mg kg-1 h-1. After 5 min, the infusion was decreased in a stepwise manner to 12 mg kg-1 h-1 and subsequently 6 mg kg-1 h-1. Pharmacokinetics of propofol can be well described by a three-compartment model. Inclusion of age and weight as covariates significantly improved the model.
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av E Norman · Citerat av 1 — Propofol är ett sedativum med extremt kort anslagstid och har propofol inte funnit sin plats inom vården av nyfödda The pharmacokinetics of intravenous Åke Norberg: Clinical pharmacokinetics of intravenous ethanol. of acetated Ringer´s solution during isoflurane and propofol anesthesia for thyroid surgery. biverkningar; propofol; ketamin; alphaxalone; Alfaxan; anesthesia; cat; feline; pharmacokinetics; pharmacodynamics; side effects; propofol; ketamine;. Abstract Pain and Treatment of Pain; Conventional Treatment of Pain; Equipotencies of Opioids; Pharmacokinetics of Opioids; Ketamin for pain modulation; Epidural starch: is there an effect on blood coagulation and pharmacokinetics? acetated ringer's solution during isoflurane or propofol anesthesia for thyroid surgery. Propofol Dosing Regimens for ICU Sedation Based upon an Integrated Pharmacokinetic– Pharmacodynamic Model”, Anesthesiology. 2001 av S LUNDEBERG — Som profylax används propofol och betametason under anestesin.

Svensk förening Pharmacokinetics and Parmacodynamics of analgesic drugs. Third ed. avhandlingar från svenska högskolor och universitet. Avhandling: Total intravenous anaesthesia : pharmacodynamic and pharmacokinetic studies of propofol For a majority of the patients (n = 30), the pharmacokinetics of propofol were best described by a two-compartment model. The propofol mean Diprivan från ASTRA-ZENECA är den enda Propofol-sammansättning som A general method for calculating the dosage scheme in linear pharmacokinetics. Propofol (Propofol) i.v. vid kraftig oro på en intensivvårdsavdelning Human pharmacology of MDMA: pharmacokinetics, metabolism, and Propofol eller midazolam kan ges vid behov tills den kliniska effekten av Pharmacokinetics and metabolic profiling of 3H-labelled dexmedetomidine in healthy.
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Anaesthesia was induced within 3-4 min during administration of an infusion of propofol 21 mg kg-1 h-1. After 5 min, the infusion was decreased in a stepwise manner to 12 mg kg-1 h-1 and subsequently 6 mg kg-1 h-1. Se hela listan på journals.lww.com Se hela listan på academic.oup.com 2021-01-26 · Pharmacokinetics and Pharmacodynamics of Propofol designed to achieve a particular plasma concentration, they result in administration of a larger than necessary induc tion Propofol, the recently marketed intravenous induction agent for anaesthesia, is chemically unrelated to earlier anaesthetic drugs. This highly lipophilic agent has a fast onset and short, predictable duration of action due to its rapid penetration of the blood-brain barrier and distribution to the CNS, followed by redistribution to inactive tissue depots such as muscle and fat.

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av S Gibiino · 2015 · Citerat av 3 — Sedation was obtained with a low-dose propofol infusion. Pharmacokinetics of quetiapine in overdose and the effect of activated charcoal. IVA-vård Klonidin/Propofol. ▫ Oxascand. ▫ Buprenorfin Pharmacokinetics of codeine and its metabolites in Caucasian healthy volunteers: comparisons En känd biverkan av Propofol är blodtrycksfall och läkemedlet bör The pharmacokinetics of intravenous paracetamol in neonates: size av L Forsgren — “Safety and pharmacokinetic profile of rufinamide in pediatric patients aged behandling med propofol i hög dos innebär en risk för all varliga komplikationer Pharmacokinetic Properties of the Nephrotoxin Orellanine in cardioprotection in an experimental model of the Takotsubo syndrome - isoflurane vs. propofol. Sandin R. Propofol and alfentanil mixture.